Yaqi Hu

Third-year Ph.D. student · University of California, Irvine

Yaqi Hu

I build machine learning methods for pathology images and spatial omics. Recent work predicts single-cell gene expression from histology and searches the non-coding genome for causal variants.

Advised by Prof. Jing Zhang

Open to summer research internships

Portrait of Yaqi Hu

News

  1. NeurIPS 2026sMMC-22M: A Context-Aware Dataset and Benchmark for Single-Cell Spatial Transcriptomics was accepted to the main track.
  2. KDD 2026MUGO: Differentiable Combinatorial Optimization for Causal Variant Discovery in the Non-coding Genome was published in the KDD 2026 proceedings.
  3. CIKM 2026STMoE: Multi-Scale Mixture-of-Experts for Single-Cell Gene Expression Prediction from Histology was accepted.
  4. JudgeJudged oral and poster presentations at the 2026 UC Irvine Undergraduate Research Symposium.
  5. JudgeJudged student projects in AI, machine learning and software engineering at IrvineHacks.
  6. ACML 2024Presented our lab’s paper Understanding Transcriptional Regulatory Redundancy by Learnable Global Subset Perturbations in Hanoi. Best Student Paper Award.

Selected publications

All publications ↗
  1. Main figure
    coming soon
    NeurIPS 2026Main track

    sMMC-22M: A Context-Aware Dataset and Benchmark for Single-Cell Spatial Transcriptomics

    Author list coming with the camera-ready version

    A single-cell spatial transcriptomics dataset and benchmark that keeps each cell’s tissue context.

    Paper and code after camera-ready
  2. Main figure
    coming soon
    CIKM 2026Rome, Italy

    STMoE: Multi-Scale Mixture-of-Experts for Single-Cell Gene Expression Prediction from Histology

    Author list coming with the camera-ready version

    Predicts single-cell gene expression from histology images, with experts that look at the tissue at several scales.

    Paper and code after camera-ready

Talks & Activities

All talks & activities ↗
  1. Judge2026 UC Irvine Undergraduate Research Symposium

    Reviewed audition videos and judged oral spotlight and poster presentations. Irvine, CA.

  2. JudgeIrvineHacks

    Evaluated student hackathon projects in AI, machine learning and software engineering. Irvine, CA.

  3. TalkConference talk and poster, ACML 2024

    Understanding Transcriptional Regulatory Redundancy by Learnable Global Subset Perturbations. Hanoi, Vietnam. Best Student Paper Award.

Teaching

Details ↗
  • ICS 6D Discrete Mathematics for CSTeaching Assistant · UC Irvine · Fall 2026, Spring 2026, Spring 2025
  • ICS 45C Programming in C/C++Teaching Assistant · UC Irvine · Winter 2025
  • DSCI 552 Machine Learning for Data ScienceCourse Producer · USC · Spring 2024, Fall 2023

Education

  • Ph.D., University of California, IrvineIn progress
  • M.S. Computer Science, University of Southern California2023 – 2024
  • B.Sc. Computer Technology and Its Application, Macau University of Science and Technology2018 – 2022